Performance Lab PL-Immune Review

Performance Lab PL-Immune Review: Quick Summary

If you’re looking for a supplement to help boost your immune system, then Performance Lab PL-Immune is something that I’ve been taking daily since the pandemic started.

Luckily, I haven’t been ill yet. And the science behind PL-Immune’s ingredients certainly reinforce its effectiveness in keeping you healthy.

Since I first tried it, it’s become a staple in my backpack that I travel around with.

Performance Lab PL Immune

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Ever since the Covid-19 pandemic, traveling the world has been seen as a risk to your health. So, it’s only natural for me to start looking for ways to boost my immune system and health.

If I’m at home, I drink Yakult for the probiotics and exercise at least 3 times per week. But while I’m traveling around different countries, it’s not always easy to exercise as much as I would like (and I can’t just take Yakult everywhere since it needs to be kept in a fridge).

As a result, I rely on supplements to keep my immune system and health guard up as much as possible; I take a multivitamin daily, as well as Performance Lab PL-Immune – a new immune system booster supplement I found.

In this review, I’ll take you through my personal experience using it, as well as other details such as analyzing its ingredients and more.

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Performance Lab PL-Immune Ingredients

The box showing the supplement facts label and ingredients of Performance Lab PL-Immune
The box of Performance Lab PL-Immume showing its ingredients.

I always start a review of supplements that I use by analyzing the ingredients.

This is because a product is only as effective as what’s inside – yep, it really is what’s inside that counts when choosing a supplement

To put it bluntly: if a product contains clinical proven ingredients, then it’ll be worth trying out. If it contains gimmicky ingredients that aren’t proven to work in clinical studies, then you’ll want to give it a miss.

The good news is that I’ve come to really like Performance Lab supplements due to how backed up they are by science. This is a company that never “blindly formulates” their supplements, but instead has their R&D department spend months looking at individual ingredients in terms of their effectiveness.

Anyway, let me take you through the ingredients in Performance Lab PL-Immune.

Vitamin D

By now, the world is pretty informed enough with nutrition that almost everyone knows Vitamin D is good for your health.

But, unfortunately, the majority of people living in not-so-sunny places probably aren’t getting enough Vitamin D daily…

This is because It’s said that 50-90% of this vitamin is obtained through the skin via sunlight, with the rest being from our diet. So, those living in places that aren’t blessed with all-year-round sun are likely to be deficient.

To prove that the above statement, a clinical study conduced in January 20211 stated:

“Vitamin D deficiency is a global public health issue. About 1 billion people worldwide have vitamin D deficiency, while 50% of the population has vitamin D insufficiency”

The same study mentions that those over 65 years old should be consuming 1000IU of Vitamin D through their diet or supplements, while those under 65 should be taking up to 800IU.

Performance Lab PL-Immune contains 20 mcg (equivalent to 1000IU) of Vitamin D, so even those over 65 years of age will be consuming the recommended amount to stay healthy; it’s this kind of detail in terms of ingredients and dosages in Performance Lab supplements is what keeps us coming back for more.

For additional vitamin and mineral support, we also make sure to take a multivitamin supplement (check out my Performance Lab Multivitamin Review for more info).

Vitamin C

You don’t need me to tell you the many health benefits of Vitamin C. Even before the pandemic, many of you were still taking Vitamin C anyway.

But since you’re here, let me show you the conclusion of a clinical study that examined the link between Vitamin C and immune function2:

“Ensuring adequate intake of vitamin C through the diet or via supplementation, especially in groups such as the elderly or in individuals exposed to risk factors for vitamin C insufficiency, is required for proper immune function and resistance to infections”

That pretty much sums up this section. So, let’s move onto the next ingredient in Performance Lab PL-Immune.


Now, this is one ingredient that most people won’t have heard about before, so let us explain; Selenium is an essential mineral (meaning your body doesn’t produce it naturally, so relies on you obtaining it through your diet or supplementation).

It has a chemical symbol “Se” – but you’re not interested in that…instead, I’ll show you a summary from a clinical study that assessed Selenium’s effectiveness in boosting your immune system3:

“Overall, there is considerable evidence strengthening the notion that Se affects different types of immune responses in different ways”

Again, it’s clear to see that Performance Lab’s R&D department has completed their due dilligence when formulating PL-Immune. It’s great to see.


Back to another nutrient that you’ve most likely heard about before.

Zinc is another essential mineral that perhaps doesn’t get the limelight that it should; it’s important in men for helping to regulate testosterone, as well as being needed for immune function, metabolism and growth.

To prove this, a clinical study conducted on Zinc’s effect on human immune function concluded with this statement4:

“zinc deficiency causes severe impairment of immune function, comprising the adaptive as well as the innate immune system”

As a result, it’s certainly important to make sure you consume enough zinc naturally through your diet or by supplementing with it.

LC-Plasma (IMMUSE™)

If there’s one ingredient in Performance Lab PL-Immune that you’ll never have heard about, it’ll be this one.

Also known as Lactococcus lactis, LC-Plasma is a probiotic that’s known for being able to encourage your body to produce more pDC, which then primes your immune system to be capable of fighting potential danger better5.

So, to summarize the above sentence and make it easily understandable: LC-Plasma enables your body to produce more pDC which then strengthens your immune system.

In fact, out of hundreds of probiotics and bacteria researched, it was found that LC-Plasma was the only one that was capable of boosting your immune system – pretty cool, right?

More interestingly a study found that LC-Plasma:

“Enhances Lung Immune Response Resulting in Protection from Murine Parainfluenza Virus Infection”6

The fact that LC-Plasma has been found to help protect you from a virus infection is super important in the current situation. Great work again by Performance Lab in finding this ingredient and adding it into their immune system booster supplement.

Out of all the ingredients found in PL-Immune, we believe this one to be the “star of the show” that you won’t find in other supplements.

Setria® Glutathione

Back to an ingredient that you probably haven’t heard of before.

Setria is a patented form of Glutathione; it’s an antioxidant naturally found in plants, fungi, animals as well as every cell in your body.

Glutathione is an important nutrient in your body and is responsible for many functions such as; making DNA, helping your liver and gallbladder deal with fats, and more importantly, supporting your immune function.

A clinical study also found that there is a strong correlation between healthy humans and optimal glutathione levels:

“The available evidence suggests that the lymphocytes from healthy human subjects have, on average, an optimal glutathione level”7

As a result, it’s always a good idea to ensure you have the right amount of glutathione in your diet. Which is why Performance Lab have added this ingredient into PL-Immune.

Click here to view lowest price for Performance Lab PL-Immune

My Personal Experience with Performance Lab PL-Immune (Review)

Performance Lab PL Immune

In all of my reviews of products that I use, I always make sure to add my own personal experience of using them; I believe this makes my reviews stand out from the other “less personal” reviews to add more quality to them, and I hope you agree too!

Anyway, I’d been using Performance Lab supplements for over 1 year now. Most notably their multivitamin and natural sleep aid (check my Performance Lab Sleep Review if you’re interested).

I received an email informing me of the release of PL-Immune towards the start of the year, in January 2021. And since I liked their other products and wanted additional health support to allow me to begin traveling around again, I bought this product to test out.

PL-Immune isn’t a stimulant, so don’t expect an “energy boost” like with a caffeine pill or coffee

Whenever I try a new multivitamin or other non-stimulant supplement, one thing I never look out for is if I experience an instant boost of energy; this is because multivitamins and PL-Immune do not contain any caffeine or sugar, so have no reason to boost your energy levels immediately.

That being said, after taking PL-Immune for a few months, I did notice that I wasn’t getting as “fatigued” towards the end of the day as I was before. This is most likely due to it containing an optimal amount of Vitamin D, which is known for having a variety of benefits including improving fatigue8.

I haven’t been ill since taking PL-Immune

Now, this is a pretty big statement. But it’s true – I haven’t had so much as a runny nose since taking this immune system booster supplement.

I’ll point out that I do also take a multivitamin for additional nutrition support. So it may be the combination of PL-Immune and a multivitamin that keeps you fully protected.

The science behind this supplement checks out, so it’s not a huge surprise…

…But that’s not to say that PL-Immune will make you invincible

While taking PL-Immune, it’s still necessary to follow optimal hygiene practises (eg. washing your hands/sanitizing your hands before eating etc). Don’t take any chances with your health, even when taking an immune system booster supplement.

I’ve actually just ordered another 4 months worth of PL-Immune for $147 with free shipping, so if you’re wondering whether I’d buy it again – the answer is yes.

Click here to view lowest price for Performance Lab PL-Immune

Performance Lab PL-Immune Review Conclusion

I’ll admit, before the pandemic and the whole world went into lockdown, I don’t think that I would have considered an immune system booster to take daily.

But that’s just the situation we’re living in.

And I really want to get out and begin traveling the world again – knowing that I’m doing everything I can to stay healthy and safe. Performance Lab PL-Immune helps me do just that.

That being said, I do still take every measure possible in order to stay protected from Covid-19 and other illnesses. As well as taking this supplement; I take a multivitamin, try my best to exercise regularly, wash/sanitize my hands at every opportunity, wear face masks in public places such as malls and convenience stores, and drink tons of water each day.

Ultimately, there’s a lot of science backing up the effectiveness of PL-Immune (as I’ve shown you in this review). So, you can be confident that this product will support your immune function so you can go back to living life as normally as possible, sooner rather than later.

Click here to view lowest price for Performance Lab PL-Immune


  1. Sizar O, Khare S, Goyal A, et al. Vitamin D Deficiency. [Updated 2021 Jan 3]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan.

  2. AC Carr. Vitamin C and Immune Function. Nutrients. 2017 Nov; 9(11): 1211.

  3. PR Hoffman. The influence of selenium on immune responses. Mol Nutr Food Res. 2008 Nov; 52(11): 1273–1280.

  4. I Wessels. Zinc as a Gatekeeper of Immune Function. Nutrients. 2017 Dec; 9(12): 1286.

  5. K Jounai. Spherical Lactic Acid Bacteria Activate Plasmacytoid Dendritic Cells Immunomodulatory Function via TLR9-Dependent Crosstalk with Myeloid Dendritic Cells. Published: April 10, 2012.

  6. K Jounai. Oral Administration of Lactococcus lactis Subsp. lactis JCM5805 Enhances Lung Immune Response Resulting in Protection from Murine Parainfluenza Virus Infection Published: March 6, 2015

  7. W Droge. Glutathione and immune function. Proc Nutr Soc. 2000 Nov; 59(4): 595-600.

  8. S Roy. Correction of Low Vitamin D Improves Fatigue: Effect of Correction of Low Vitamin D in Fatigue Study (EViDiF Study). N Am J Med Sci. 2014 Aug; 6(8): 396–402.

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